FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism

Conclusion: Our findings highlight a FA metabolism-dependent mechanism of FABP5-induced LNM. Moreover, the expression and biological function of FABP5 can be regulated by miR-144-3p in hypoxia. Our study identifies FABP5 as a potential diagnostic biomarker and therapeutic target for LNM in CCa.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Chunyu Zhang, Yuandong Liao, Pan Liu, Qiqiao Du, Yanchun Liang, Shiyin Ooi, Shuhang Qin, Shanyang He, Shuzhong Yao, Wei Wang Tags: Research Paper Source Type: research