Up-regulation of hypoxia-inducible factor antisense as a novel approach to treat ovarian cancer

Conclusion: Induction of hypoxic stress responses through inhibition of gp130 represents a novel approach to design effective anticancer treatments in combination with standard-of-care chemotherapy in OC and the efficacy reported here strongly supports their clinical development.

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Tiangong Lu, Jianming Tang, Binita Shrestha, Blake R. Heath, Li Hong, Yu L. Lei, Mats Ljungman, Nouri Neamati Tags: Research Paper Source Type: research