GSE137411 Bimodal Adenine and Cytosine CRISPR Base Editing on DNA

Contributors : Julian Grunewald ; Caleb LareauSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAdenine and cytosine base editors (ABEs and CBEs) represent a new genome editing technology that allows the programmable installation of A-to-G or C-to-T alterations on DNA. We engineered Streptococcus pyogenes Cas9-based adenine and cytosine base editor (SpACE) that enables efficient simultaneous introduction of A-to-G and C-to-T substitutions in the same base editing window on DNA.

Source: GEO: Gene Expression Omnibus - July 2, 2020 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research