The cost of Hypertensive Disorders of Pregnancy to the Australian Healthcare System
Publication date: Available online 1 July 2020Source: Pregnancy HypertensionAuthor(s): Haylee Fox, Emily J. Callander
Publication date: Available online 31 July 2020Source: Pregnancy HypertensionAuthor(s): Katherine M. Johnson, Aaron J. Specht, Jessica M. Hart, Saira Salahuddin, Adrienne L. Erlinger, Michele R. Hacker, Alan D. Woolf, Marissa Hauptman, S. Ananth Karumanchi, Blair J. Wylie, Karen O'Brien
Am J Perinatol DOI: 10.1055/s-0040-1714421 Objective We sought to quantify the distribution of stillbirths by gestational age (GA) in a contemporary cohort and to determine identifiable risk factors associated with stillbirth prior to 32 weeks of gestation. Study Design Population-based case-control study of all stillbirths in the United States during the year 2014, utilizing vital statistics data, obtained from the National Center for Health Statistics. Distribution of stillbirths were stratified by 20 to 44 weeks of GA, in women diagnosed with stillbirth in the antepartum period. Pregnancy characteristics...
ConclusionThe current study found a high prevalence of DPN and it was found to be significantly associated with duration of diabetes, poor glycaemic control and nephropathy.
Publication date: October 2020Source: Pregnancy Hypertension, Volume 22Author(s): C. Birdir, L. Fox, L. Droste, M. Frank, J. Fryze, A. Enekwe, A. Köninger, R. Kimmig, B. Schmidt, A. Gellhaus
Conclusions. Overall, these data show that pregnancy after KT has no effect on long-term graft survival and only a possible effect on graft function within 2 years postpartum. This might be due to publication bias. No significant differences were observed between pre- and postpartum SCr at longer follow-up intervals.
Publication date: September 2020Source: European Journal of Obstetrics &Gynecology and Reproductive Biology, Volume 252Author(s): Valentina Pecoraro, Tommaso Trenti
Conclusions: Tac treatment during conception, pregnancy and lactation seems to be relatively safe. Due to pharmacokinetic changes during pregnancy, a higher Tac dose might be indicated to maintain target concentrations. However, more evidence is needed to make recommendations on both Tac dose adjustments and alternative matrices than whole-blood for TDM of Tac during pregnancy. MPA treatment in men during conception seems to have no adverse effect on pregnancy outcomes, whereas MPA use in women during conception and pregnancy is strongly discouraged.
Chronic hypertension during gestation is associated with an increased risk of adverse pregnancy outcomes including pre-eclampsia, fetal growth restriction and preterm birth. Research into new chemotherapeutic regimes for the treatment of hypertension in pregnancy is limited due to concerns about fetal toxicity and teratogenicity, and new therapeutic avenues are being sought in alternative physiological pathways. Historically, generation of the vasodilator nitric oxide was believed to be solely from L-arginine by means of nitric oxide synthase enzymes. Recently, a novel pathway for the reduction of dietary inorganic nitrate...
ABSTRACTIntroductionIntraabdominal pressure (IAP) is related to clinical outcome of patients. It is measured as intravesical pressure through Foley catheter, in supine position. During pregnancy, there is data showing elevated IAP, and also a suggestion that it may be a false increase due to pressure on urinary bladder by the gravid uterus in supine position. Additionally, it is not known whether the elevated IAP during pregnancy is merely a physiological change, or is associated with impairment of organ functions. We thus aimed to establish normal value of IAP in supine (IAPsupine) as well as 10 ° left lateral (IAPlat...
Publication date: Available online 28 July 2020Source: Pregnancy HypertensionAuthor(s): Raphaela Costa Ferreira, Marilene Brandão Tenório Fragoso, icaely Cristina dos Santos Tenório, João Victor Farias Silva, Nassib Bezerra Bueno, Marília Oliveira Fonseca Goulart, Alane Cabral Menezes de Oliveira