Hypoxia-induced miR-3677-3p promotes the proliferation, migration and invasion of hepatocellular carcinoma cells by suppressing SIRT5.

In conclusion, the overexpression of miR-3677-3p mediated SIRT5 inhibition, which could increase proliferation, migration and invasion of HCC in hypoxic microenvironments.
PMID: 32596968 [PubMed - as supplied by publisher]

Source: J Cell Mol Med - June 27, 2020 Category: Molecular Biology Authors: Yao B, Li Y, Niu Y, Wang L, Chen T, Guo C, Liu Q Tags: J Cell Mol Med Source Type: research