Histopathologic findings in women undergoing hysteroscopic resection of endometrial polyps and uterine myomas.

HISTOPATHOLOGIC FINDINGS IN WOMEN UNDERGOING HYSTEROSCOPIC RESECTION OF ENDOMETRIAL POLYPS AND UTERINE MYOMAS. Acta Clin Croat. 2019 Dec;58(4):627-631 Authors: Soljačić Vraneš H, Djaković I, Vrljičak M, Đurić Orsag N, Kuna K, Kraljević Z, Leniček T, Brlečić I Abstract The aim of our study was to determine the prevalence of endometrial premalignant and malignant lesions in women undergoing hysteroscopy and to identify anthropologic factors related to the presence of malignancy. Data on 3470 women with submucosal myomas or endometrial polyps suspected on ultrasound were retrospectively analyzed. Hysteroscopy was performed in all these women in order to make a more precise diagnosis. Histologic analysis of endometrial samples obtained during hysteroscopy was used to confirm the diagnosis. Statistical analysis was performed using the SPSS 20.0.0 software. The mean age of study women was 49.1±13.3 years. The number of procedures performed due to the referral diagnosis of endometrial or submucosal myoma significantly increased over the 16-year study period. A significantly higher number of women had a benign histopathologic diagnosis. Histologic analysis revealed malignancy in 67 women. The youngest woman and oldest woman with malignant findings was aged 32 and 75, respectively. A significantly higher number of women with atypical hyperplasia and malignancy were in menopause. A comparable number of women with different histologic finding...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research

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, Török P Abstract Introduction: Most endometrial polyps represent focal hyperplasia of the endometrium. Endometrial polyps can be diagnosed by ultrasound, hysterocontrast sonography, hysterosalpingography, endometrial biopsy, and uterine curettage, but diagnostic hysteroscopy is considered the gold-standard method, with the greatest sensitivity and specificity and also with the opportunity for treatment at the same time.Study design: A retrospective study was conducted on 424 patients between 2006 and 2018. The polyps were verified during diagnostic hysteroscopy and were removed by resectoscopy or curet...
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
Abstract Endometrial polyps are a common finding, with a prevalence of about 40%, and are usually diagnosed incidentally as most are asymptomatic. Symptomatic polyps usually present with abnormal uterine bleeding and/or sub-fertility. About 25% of polyps resolve spontaneously if managed conservatively. The usual management of endometrial polyps, symptomatic or asymptomatic, is polypectomy, performed primarily to exclude malignancy within the polyp despite the overall risk of malignancy being low (about 3%). The main risk factors for malignancy are menopause and abnormal uterine bleeding, with hypertension, obesity...
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
Abstract Menopause is characterized by permanent cessation of menstrual periods and is clinically diagnosed after 12 months of complete amenorrhea. It occurs at a median age of 51 years alongside the physiological process of aging, although it can happen at an earlier age for other medical conditions or after surgery (surgical menopause). Due to reduced circulating estrogens and progesterone, the reproductive organs undergo progressive atrophy. This physiologic process of aging is also present at an endometrial level; without the cyclic hormonal actions of the menstrual cycle, the endometrium during ...
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
We describe the first case of ovarian SST with estrogen excess with both clinical and serological evidence in a postmenopausal woman. Patient concerns: A 70-year-old female who referred menopause 14 years ago was admitted with postmenopausal bleeding for 3 months. Ultrasonography revealed thickened endometrium of 6 mm and no adnexal masses. An elevated serum estradiol level of 49.78 ng/L was revealed in laboratory examination with normal ranges less than 27.25 ng/L in postmenopausal women. Diagnoses: The final histology diagnosis is SST of left ovary and endometrial hyperplasia with polyps. Interventions: Laparo...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
ConclusionThe utilization of a stone retrieval basket is a novel and effective method for retrieving a wide based endometrial polyp following incomplete resection with hysteroscopic scissors.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Objective: We analyzed tamoxifen use as a malignancy risk factor in women with endometrial polyps. Methods: This retrospective study included 675 women who underwent hysteroscopic polypectomy in 2010 to 2015 at the University of Campinas. Women were divided into tamoxifen use (n = 169) and no tamoxifen use (n = 506) groups. The primary outcome was endometrial cancer prevalence. Dependent variables included age, parity, years since menopause, presence of abnormal uterine bleeding, endometrial pattern on hysteroscopy, and endometrial thickness. Results: There were seven cases of endometrial cancer in the tamo...
Source: Menopause - Category: OBGYN Tags: Original Articles Source Type: research
We report a case of misdiagnosed endometrial cancer by D&C, but with a positive cytopathological finding. Following that, a meta-analysis including 4,179 patients of endometrial diseases with cyto-histopathological results was performed to assess the value of the endometrial cytological method in endometrial cancer diagnosis. The pooled sensitivity and specificity of the cytological method in detecting endometrial atypical hyperplasia or cancer was 0.91[95% confidence interval (CI) 0.74–0.97] and 0.96 (95% CI 0.90–0.99), respectively. The pooled positive likelihood ratio and negative likelihood ratio was 25.4 (...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 15 April 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Anna Uglietti, Laura Buggio, Marilena Farella, Francesca Chiaffarino, Dhouha Dridi, Paolo Vercellini, Fabio ParazziniAbstractBackgroundEndometrial polyps are a common condition. The risk of malignancy has often led to an overtreatment with high health care costs and huge psychological distress.ObjectiveWe conducted a systematic review and a meta-analysis in order to estimate the prevalence of premalignant and malignant lesions in women undergoing hysteroscopic polypectomy.Data sourceWe d...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Publication date: Available online 4 January 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Shimrit Shor, Moty Pansky, Ron Maymon, Zvi Vaknin, Noam SmorgickABSTRACTStudy ObjectiveTo investigate whether hysteroscopic features can contribute to the diagnosis of malignancy in endometrial polyps.DesignRetrospective review.SettingObstetrics and gynecology department.PatientsAll women who underwent operative hysteroscopy for the removal of endometrial polyps between January 2012 and September 2017. Their medical records were reviewed, and information on medical, surgical, and obstetric history and hysteroscopic f...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: Available online 29 January 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Ettore Cicinelli, Stefano Bettocchi, Dominique De Ziegler, Vera Loizzi, Gennaro Cormio, Marco Marinaccio, Giuseppe Trojano, Francesco Maria Crupano, Roberta Francescato, Amerigo Vitagliano, Leonardo RestaAbstractStudy objectiveTo investigate the correlation between endometrial polyps (EPs) and chronic endometritis (CE).DesignSingle-center retrospective case-control study.SettingAcademic Centre.PatientsA total of 480 premenopausal women with abnormal uterine bleeding (AUB) were enrolled. Group A included 240 women su...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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