Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma

Conclusion: Our results showed hypoxia upregulated the protein levels of VEGFA and ANGPT2 in lung cancer cell lines, and the roles of VEGFA and ANGPT2 were distinct in ADC and SQC. Combined detections of VEGFA and ANGPT2 may be valuable prognostic biomarkers for ADC and double block of VEGFA and ANGPT2 may improve therapeutic outcome.

Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Shuang Qin, Ming Yi, Dechao Jiao, Anping Li, Kongming Wu Tags: Research Paper Source Type: research