Aberrant AFP expression characterizes a subset of hepatocellular carcinoma with distinct gene expression patterns and inferior prognosis
Conclusion High expression of AFP defined a subtype of liver cancer with distinct gene expression profiles and clinical features. De-methylation of cytosine from CpG di-nucleotides in AFP promoter may be the cause of AFP re-expression in adult human liver cancer tissue.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Wei Chen, Jianjun Peng, Jinning Ye, Weigang Dai, Guanghua Li, Yulong He Tags: Research Paper Source Type: research
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