Rhein induces liver cancer cells apoptosis via activating ROS-dependent JNK/Jun/caspase-3 signaling pathway

Conclusions: The present study showed that Rhein promotes apoptosis via regulating ROS/JNK/Jun/caspase-3 signaling pathway both in HepG2 and Huh7 cells. Rhein may be a promising therapeutic candidate for the treatment of liver cancer.

Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Aili Wang, Huihong Jiang, Yuanyuan Liu, Jing Chen, Xue Zhou, Chenxi Zhao, Xia Chen, Mobin Lin Tags: Research Paper Source Type: research