LRG1 Suppresses Migration and Invasion of Esophageal Squamous Cell Carcinoma by Modulating Epithelial to Mesenchymal Transition

Conclusion/Significance: LRG1 suppresses ESCC cell migration and invasion via negative modulation of TGFβ signaling and EMT. Down-regulation of LRG1 in ESCC patients may favor tumor metastasis and disease progression.

Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Ninggang Zhang, Yaqiong Ren, Yusheng Wang, Lei Zhao, Bin Wang, Nina Ma, Zhengxing Gao, Bangwei Cao Tags: Research Paper Source Type: research