MiR-34a-5p Inhibits Proliferation, Migration, Invasion and Epithelial-mesenchymal Transition in Esophageal Squamous Cell Carcinoma by Targeting LEF1 and Inactivation of the Hippo-YAP1/TAZ Signaling Pathway

Conclusion: Our results indicate miR-34a-5p inhibits proliferation, migration, invasion and EMT in ESCC by targeting LEF1 and suppressing the Hippo-YAP1/TAZ signaling pathway, which may provide a new antitumor strategy to delay ESCC progress.

Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Xinyu Wang, Yue Zhao, Qijue Lu, Xiang Fei, Chaojing Lu, Chunguang Li, Hezhong Chen Tags: Research Paper Source Type: research