Peroxiredoxins and Immune Infiltrations in Colon Adenocarcinoma: Their Negative Correlations and Clinical Significances, an In Silico Analysis

Conclusions: Late diagnosis indicated poor prognosis in COAD and dy-regulated PRDXs w might be new markers for its early diagnosis. Age was prognostic and should be considered in the treatments of the older patients. Dy-regulated PRDXs were negatively correlated with immune infiltration levels. CD4+ T cell and CD8+ T cell infiltrations were prognostic in COAD and their potential as immune targets needed further investigation.

Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Xiuzhi Zhang, Fenglan Gao, Ningning Li, Jinzhong Zhang, Liping Dai, Hongmei Yang Tags: Research Paper Source Type: research