Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study

ConclusionThis work showed that the techniques described here are sufficient for this type of study. However, future studies involving the use of more selective pharmacological agents and/or genetic manipulations will be key to advance a mechanistic understanding of cardiac autonomic regulation in DS.

Source: Physiological Reports - June 18, 2020 Category: Physiology Authors: Adriano L. Roque, Mark W. Johnson, Melissa R. Stasko, Luiz C. Abreu, Talita D. Silva, Alberto C.S. Costa Tags: ORIGINAL RESEARCH Source Type: research