Central motor conduction time reveals upper motor neuron involvement masked by lower motor neuron impairment in a significant portion of patients with amyotrophic lateral sclerosis.

CONCLUSIONS: CMCT shows UMN dysfunction in ALS patients without clinical UMN impairment. SIGNIFICANCE: TMS still has diagnostic utility in a significant portion of ALS patients. PMID: 32593964 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - Category: Neurology Authors: Tags: Clin Neurophysiol Source Type: research