Differentiating PNES from epileptic seizures using conversational analysis on French patients: A prospective blinded study.

The objective of our study was to evaluate the contribution of linguistic analysis in the differential diagnosis between ES and PNES in a French patient population. During an extended video-electroencephalogram (video-EEG) monitoring, 13 patients presented PNES and 19 patients with ES. Two neurologists blindly and independently analyzed the interview of each patient. Rater 1 predicted the correct diagnosis in 27 of 32 patients (84%) and Rater 2 in 28 of 32 patients (88%). Interrater reliability of qualitative analysis was satisfactory (k = 0.68, interrater agreement = 84.4%). Using a simplified DSA, Rater 1 and Rater 2 would have correctly diagnosed 88% (28/32 patients) and 91 % (29/32) of the cases, respectively. Our blinded prospective study confirms the diagnostic value of conversational analysis, performed by neurologists, to differentiate PNES from ES in French-speaking patients.
PMID: 32599432 [PubMed - as supplied by publisher]

Source: Epilepsy and Behaviour - June 25, 2020 Category: Neurology Authors: Biberon J, de Liège A, de Toffol B, Limousin N, El-Hage W, Florence AM, Duwicquet C Tags: Epilepsy Behav Source Type: research