Targeted Optical Imaging of the Glucagonlike Peptide 1 Receptor Using Exendin-4-IRDye 800CW

Conclusion: These data provide the first in vivo evidence of the feasibility of targeted fluorescence imaging of GLP-1R–positive lesions. Intraoperative lesion delineation using exendin-4-IRDye 800CW could benefit open as well as laparoscopic surgical procedures for removal of insulinomas and focal lesions in CHI.

Source: Journal of Nuclear Medicine - June 30, 2020 Category: Nuclear Medicine Authors: Boss, M., Bos, D., Frielink, C., Sandker, G., Ekim, S., Marciniak, C., Pattou, F., van Dam, G., van Lith, S., Brom, M., Gotthardt, M., Buitinga, M. Tags: Basic Source Type: research