The in vitro anti-cancer activities of Ocimum sanctum leaf extracts (holy basil)

In this study, a researcher at Government Degree College, Khairatabad in India investigated the anti-cancer activity of plant suspension cultures of Ocimum sanctum (holy basil) against lung cancer. Key findings were published in the International Journal of Green Pharmacy. Ethanol, acetone and aqueous leaf extracts of O. sanctum were used to treat human lung cancer (A549) cells....
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Publication date: Available online 4 July 2020Source: European UrologyAuthor(s): Friedemann Krentel, Roland Seiler
Source: European Urology - Category: Urology & Nephrology Source Type: research
Publication date: October 2020Source: Pharmacological Research, Volume 160Author(s): Shengda Luo, Jiahui Xu, Zebo Jiang, Lei Liu, Qibiao Wu, Elaine Lai-Han Leung, Alex Po Leung
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 4 July 2020Source: Molecular ImmunologyAuthor(s): Dehai Che, Shuai Zhang, Zihan Jing, Lihua Shang, Shi Jin, Fang Liu, Jing Shen, Yue Li, Jing Hu, Qingwei Meng, Yan Yu
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
Authors: Fujino T, Suda K, Mitsudomi T Abstract INTRODUCTION: MET aberrations, including MET exon 14 skipping mutation and amplification, are present in ~5% of non-small cell lung cancer (NSCLC) cases, and these levels are comparable to the frequency of ALK fusion. MET amplification also occurs as an acquired resistance mechanism in EGFR-mutated NSCLC after EGFR tyrosine kinase inhibitors (TKI) treatment failure. Therefore, the development of therapies for activated MET is urgently needed. AREAS COVERED: This review summarizes (1) the mechanisms and frequencies of MET aberrations in NSCLC, (2) the efficacies an...
Source: Expert Opinion on Emerging Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Emerg Drugs Source Type: research
LUNG CANCER is a serious disease. Around 47,000 people are diagnosed with the condition every year in the UK. And there's a sign when you're eating that could indicate that you have it too.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
This study aimed to compare the prevalence and associated factors of depressive disorder between patients with head and neck cancer (HNC) and those with lung cancer (LC). DESIGN: This st...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
Isolation of Oxyberberine and β-Sitosterol from Berberis lycium Royle Root Bark Extract and In Vitro Cytotoxicity against Liver and Lung Cancer Cell Lines. Evid Based Complement Alternat Med. 2020;2020:2596082 Authors: Anwar MA, Tabassam S, Gulfraz M, Sheeraz Ahmad M, Raja GK, Arshad M Abstract Berberis lycium Royle has been traditionally used to cure rheumatism, eye and ear diseases, malarial fever, diabetes, stomach disorders, and skin diseases. There is a least amount of data available on cytotoxic capacity of Berberis lycium from Pakistani origin, so on this basis, the present study was aimed ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
AbstractPurposeAs the number of cases of early lung cancer in Japan grows, an analysis of the present status of surgical treatments for clinical stage IA lung cancer using a nationwide database with web-based data entry is warranted.MethodsThe operative and perioperative data from 47,921 patients who underwent surgery for clinical stage IA lung cancer in 2014 and 2015 were obtained from the National Clinical Database (NCD) of Japan. Clinicopathological characteristics, surgical procedure, mortality, and morbidity were analyzed, and thoracotomy and video-assisted thoracic surgery (VATS) were compared.ResultsThe patients com...
Source: Surgery Today - Category: Surgery Source Type: research
In this study, we examined the safety, therapeutic results, and prognosis of surgical treatment for lung cancer patients over 85 years of age.MethodsAmong the 4446 lung cancer patients who underwent surgery at our hospital from January 1997 to March 2019, we assessed 320 patients (7.2%, Group A, aged 80 –84 years) and 74 patients (1.7%, Group B, aged over 85 years).ResultsThe median age of the patients in Group B was 86  years. Compared to Group A, Group B had significantly more patients with a history of ischemic heart disease, lower pack-year smoking, and lobectomy and lobectomy less resection (...
Source: General Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
In conclusion, this workshop record proposed the application of a digital pathology platform to share controversial cases in educational meetings as an alternative possibility for improving the interpretation and reporting of specific histological tools. Due to the crucial role of PD-L1 TPS for the selection of patients for immunotherapy, the identification of unconventional approaches as virtual slides to focus experiences and give more detailed practical verifications of the standard quality reached may be a considerable option.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
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