US Supreme Court Strikes Down Louisiana Abortion Clinic Restrictions US Supreme Court Strikes Down Louisiana Abortion Clinic Restrictions
The US Supreme Court defended abortion rights in a major ruling on Monday by striking down a Louisiana law placing restrictions on doctors who perform the procedure, dealing a blow to anti-abortion advocates.Reuters Health Information
Publication date: Available online 30 June 2020Source: Molecular and Biochemical ParasitologyAuthor(s): Saptarshi Roy, Nikhilesh Joardar, Santi P. Sinha Babu, Larisha M. Lyndem
Publication date: Available online 30 June 2020Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Phoebe Rivory, Gregory Brown, Cathy Shilton, Richard Shine, Jan Šlapeta
Authors: Ogawa SI, Shimizu M, Kamiya Y, Uehara S, Suemizu H, Yamazaki H Abstract In vitro permeability and in vivo pharmacokinetics of pemafibrate were investigated in human intestinal and animal models untreated or pretreated with cyclosporine A or rifampicin to evaluate any drug interactions. Ratios of basal to apical apparent permeability (Papp) over apical to basal Papp in the presence of pH gradients decreased from 0.37 to 0.080 on rifampicin co-incubation, suggesting active transport of pemafibrate from basal to apical sides in intestinal models. Plasma concentrations of intravenously administered p...
In this study, we found that sesamin competitively inhibited the 7-hydroxylation activity of S-warfarin in human liver microsomes with a Ki value of 15.7 μM. In addition, the recombinant CYP2C9-dependent 7-hydroxylation activity of S-warfarin was competitively inhibited by sesamin with a Ki value of 13.1 μM. These results are consistent with the fact that sesamin is a good substrate of CYP2C9, and its activity follows Michaelis-Menten kinetics. As the plasma concentration of sesamin after its administration is usually lower than 0.01 μM, the inhibition of S-warfarin metabolism by sesamin does not ap...
Publication date: October 2020Source: Current Opinion in Virology, Volume 44Author(s): Camila R Fontes-Garfias, Coleman K Baker, Pei-Yong Shi
Publication date: Available online 30 June 2020Source: Advances in Virus ResearchAuthor(s): Daniel Nobach, Jana Müller, Dennis Tappe, Christiane Herden
Publication date: Available online 30 June 2020Source: Advances in Virus ResearchAuthor(s): Zhiqian Ma, Zhiwei Li, Linfang Dong, Ting Yang, Shuqi Xiao
Conclusions: The 36 Y-STR loci in this study have good polymorphism distributions in the Guizhou Miao population, and therefore would be a useful tool in forensic identification and male parentage testing and even pedigree investigation. PMID: 32597239 [PubMed - as supplied by publisher]
Conclusions: Both user characteristics and parenting practices were significantly associated with adolescents' initial use of Aim2Be. These findings will help inform future e-health interventions increase user engagement by identifying the characteristics of individuals who are not accessing the intervention, as well as identifying factors of the household environment that support use. PMID: 32598175 [PubMed - as supplied by publisher]
Publication date: Available online 30 June 2020Source: Small Ruminant ResearchAuthor(s): Hernán Santiago Hermida, Silvia Beatriz Colavecchia, Bárbara Fernández, Jorge Suhevic, Marcela Martinez Vivot, Guillermo Mereb, Silvia Leonor Mundo