Cytoplasmic versus nuclear THR alpha expression determines survival of ovarian cancer patients

ConclusionDepending on nuclear or cytoplasmic expression, our study shows that THR α and its isoforms 1 and 2 provide different prognostic information for ovarian cancer patients. Further investigations should analyze if THRs may represent new endocrine targets for the treatment of ovarian cancer.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research