In vivo Characterization of Four 18 F-Labeled S1PR1 Tracers for Neuroinflammation

ConclusionAmong these four new PET tracers,18F-TZ4877 showed the most favorable profile for assessing S1PR1 expression in the EAE rat model of MS. Further characterization of these radiotracers in other models of neuroinflammation is warranted to identify a promising18F-labeled tracer for imaging S1PR1in vivo.

http://link.springer.com/10.1007/s11307-020-01514-8

Source: Molecular Imaging and Biology - June 28, 2020 Category: Molecular Biology Source Type: research