Parkinson’s disease warning - the subtle changes to your voice that could be an early sign

PARKINSON'S disease symptoms develop slowly over a long time, and could be caused by nerve damage in the brain. One of the more common warning signs of the brain condition includes subtle changes to your voice when you're speaking. These are the hidden signs of Parkinson's you should know about.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 30 June 2020Source: Neuroscience LettersAuthor(s): Anoop Masih, Saumya Singh, Amol Kumar Agnihotri, Sabeena Giri, Jitendra Kumar Shrivastava, Nidhi Pandey, Hans Raj Bhat, Udaya Pratap Singh
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
The aim of this review is to summarize that most relevant technologies used to evaluate gait features and the associated algorithms that have shown promise to aid diagnosis and symptom monitoring in Parkinson's disease (PD) patients. We searched PubMed for...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
PURPOSE: People with Parkinson's are twice as likely to fall as older people within the general population. This longitudinal qualitative study was part of a larger programme of research including a randomised controlled trial to test the effectiveness of ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Conditions:   Parkinson Disease;   Constipation Interventions:   Dietary Supplement: Probiotics with prebiotic;   Dietary Supplement: Placebo Sponsor:   National University of Malaysia Completed
Source: - Category: Research Source Type: clinical trials
Discussion Though visual organization tests follow behaviour and motor performance in LBD, there is differential impairment regarding language skills.
Source: Revista de Psiquiatria Clinica - Category: Psychiatry Source Type: research
Multiple studies implicate heterozygous GBA mutations as a major genetic risk factor for Parkinson's disease (PD); however, the frequency of mutations has never been examined in PD patients from the Irish population. We prospectively recruited 314 unrelated Irish PD patients (UK Brain Bank Criteria) and 96 Irish healthy controls (without any signs or family history of parkinsonism) attending. The Dublin Neurological Institute (DNI). Complete exon GBA Sanger sequencing analysis with flanking intronic regions was performed. The GBA carrier frequency was 8.3% in PD and 3.1% in controls. We identified a number of potentially p...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Condition:   Parkinson Disease Interventions:   Device: VeNS device;   Device: Sham VeNS device Sponsors:   Neurovalens Ltd.;   R D Gardi Medical College, Ujjain Not yet recruiting
Source: - Category: Research Source Type: clinical trials
This week, I’m in conversation with science fiction novelist Marc Nash. Marc has ten Kindle books published and three in paperback. He previously joined me in 2013 with his novel Time after Time. Marc is a fan of words especially as they are the only thing a writer has in his creative palette. We also talk about what happens when books are made into films, especially when that forces fiction into ever increasing numbers of genres. One of the issues we both agreed on was the problem with sub-genres in that they exacerbate the impact of the algorythms that deliver only what people appear to be interested in, instead of...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Podcast Writing author interview Source Type: news
(Vanderbilt University Medical Center) Deep Brain Stimulation (DBS) implanted in early stage Parkinson's disease decreases the risk of disease progression and the need to prescribe multiple drugs to patients simultaneously, according to a five-year outcomes study of 30 patients released in the July 2020, issue of Neurology ® , the medical journal of the American Academy of Neurology.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
In Reply LeWitt correctly describes homovanillic acid (HVA) as an unreliable biomarker of Parkinson disease (PD) progression, but our study distinctively evaluated dopamine metabolism in response to nilotinib rather than a biomarker of PD progression, and participants were not taking monoamine oxidase B inhibitors. The hypothesis of this phase 2 study that nilotinib is a disease-modifying drug is based on previous animal data and explored a mix of biomarkers that included dopamine metabolism, α synuclein, and tau proteins. Methodologically, physiologically based population pharmacokinetics/pharmacodynamics studies sh...
Source: JAMA Neurology - Category: Neurology Source Type: research
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