Coronavirus: Could statins reduce risk of death?

Doctors are desperate for more weapons in their arsenal to treat Covid-19, which has killed almost 500,000 people worldwide in just six months. Only one drug has been proven to work so far.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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(Cell Press) The use of cholesterol-lowering drugs called statins is associated with a lower death rate and a lower incidence of mechanical ventilation in patients hospitalized with Coronavirus disease 2019 (COVID-19), researchers report June 24 in Cell Metabolism. The large-scale retrospective study also showed that mortality risk and other negative outcomes were not increased by combination therapy consisting of statins and blood pressure-lowering drugs called angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs).
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Conclusions Although clinical data supporting an influence of all these drugs on the course of the disease are limited, this is an interesting background for further research that might help unravel the complex mechanisms underlying the link between COVID-19 and diabetes.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
In the absence of an effective drug or vaccine against novel severe acute respiratory syndrome corona virus (SARS-Cov-2) till date, “repurposing approach” of old pharmaceuticals has been applied to combat against 2019-coronavirus disease (COVID-19). Hydroxychloroquine, anti-retrovirals, type-1 angiotesin receptor blockers, statin, vitamin D, melatonin etc are being tried with questionable benefits [1]. While there are intens ive debates regarding safety of different classes of antidiabetics at the advent of COVID-19 [2,3], multiple ongoing studies are evaluating the adjuvant role of various antidiaetics like di...
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Letter to the Editor Source Type: research
The following is a brief roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Conclusions: These results indicate, based upon the binding energy of pitavastatin, rosuvastatin, lovastatin, and fluvastatin, that statins could be efficient SARS-CoV-2 Mpro inhibitors. This is supported by the fact that the effects of some statins, especially pitavastatin, have a binding energy that is even greater than that of protease or polymerase inhibitors. However, further research is necessary to investigate their potential use as drugs for COVID-19. PMID: 32399094 [PubMed]
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
The COVID crisis has decimated water exercise. Can we rethink pool closures? A significant number of my older patients relied on pools for their fitness. During a pandemic, you can stay active or fit only if you have good legs and joints. Walkers, runners, and cyclists have no problem; they play outside in the Spring weather. People with bone/joint problems, fitness swimmers, and young children who normally take swim lessons this time of year are out of luck. Consider the place I swim—the Mary T Meagher Natatorium, named after Mary T, a Louisville native, who won Olympic gold in 1984. The place is an ode to Sp...
Source: Dr John M - Category: Cardiology Authors: Source Type: blogs
At the nearly the same time I posted yesterday, The Lancet published this editorial from Swedish epidemiologist Prof Johan Giesecke. Some excerpts: It has become clear that a hard lockdown does not protect old and frail people living in care homes—a population the lockdown was designed to protect. Neither does it decrease mortality from COVID-19, which is evident when comparing the UK’s experience with that of other European countries. … Everyone will be exposed to severe acute respiratory syndrome coronavirus, and most people will become infected — There is very little we can do to prevent this sp...
Source: Dr John M - Category: Cardiology Authors: Source Type: blogs
Conclusion: I did not have a clear answer for my couple. But after thinking and writing about this question it seems that the most reasonable approach in this crisis is transparent information–no matter how stark. And, crucially, we must have space for public debate. I hate this virus. I wish it never came. But we can make it worse by avoiding hard discussions on tradeoffs, the limits of modern medicine and risk. JMM P.S. I am very interested in your rebuttals to any of my assertions but will block vitriol and politicized nonsense. Related posts: The Debacle of Hydroxychloroquine and Azithromycin for ...
Source: Dr John M - Category: Cardiology Authors: Source Type: blogs
DR MICHAEL MOSLEY: A claim online said having high cholesterol might help fight the coronavirus. But as far as I can see, there is no evidence that giving up statins will protect you against Covid-19.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Transcript [00:00:00] Joe Graedon: I’m Joe Graedon. [00:00:01] Terry Graedon: And I’m Terry Graedon. Welcome to this podcast of the People’s Pharmacy. [00:00:06] Joe Graedon: You can find previous podcasts and more information on a range of health topics at PeoplesPharmacy.com.  [00:00:14] How’s your family holding up during the coronavirus pandemic? Isolation can be especially challenging for children. [00:00:22] This is the People’s Pharmacy with Terry and Joe Graedon. [00:00:33] Terry Graedon:  Children appear less susceptible than older adults to serious complications of COVID-19...
Source: Conversations with Dr Greene - Category: Child Development Authors: Tags: Dr. Greene's Blog COVID COVID-19 Viral Infection Source Type: blogs
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