High cholesterol: The plant-based supplement proven to help lower ‘bad’ cholesterol levels
HIGH CHOLESTEROL typically refers to more 'bad' cholesterol than 'good' cholesterol in the bloodstream. Would you like to change that? Here's one plant-based supplement proven to do just that.
Conclusions: Lipid metabolic process was critical in both macrophage aging and response to cholesterol thus was regarded to be associated with the occurrence and progression of AMD. Moreover, miR-714-FDFT1 may modulate cholesterol homeostasis in aged macrophages and have the potential to be a novel therapeutic target for AMD. PMID: 32626771 [PubMed - in process]
In conclusion, the present study indicated that statin use might be a protective factor for MM incidence. However, the relationship between statin use a nd MM risk requires repeated and large prospective studies to be verified.
CONCLUSIONS: PCSK-9 is independently associated with triglycerides, Lp(a) levels, and HOMA-IR, but not LDL-C, in a relatively large general population sample. PMID: 32624555 [PubMed - as supplied by publisher]
Older adults can reduce their risk for a fatal heart attack or stroke by 20 percent by taking a statin. Those over age 75 who were newly prescribed cholesterol-lowering drugs were 25 percent less likely to die.
TUESDAY, July 7, 2020 -- Older adults with healthy hearts probably would benefit from taking a cholesterol-lowering statin, a new study contends. People 75 and older who were free of heart disease and prescribed a statin wound up with a 25% lower...
MicroRNA‑133b aggravates atherosclerosis by activating the Notch signaling pathway. Mol Med Rep. 2020 Jun 11;: Authors: Han B, Li T, Zheng S Abstract The aim of the present study was to investigate the effect of miR‑133b on atherosclerosis (AS). A mouse model of AS (AS group) was established, and serum levels of total cholesterol, triglyceride, high‑density lipoprotein cholesterol and low‑density lipoprotein (LDL) cholesterol were detected. The thoracic aorta tissues were subjected to hematoxylin and eosin staining for pathological examination. Mice were intravenously injected with microRN...
In conclusion, these data suggested that the liver injury induced by ANIT may be cholestatic, while the liver injury caused in the LCA model may be hepatocellular. Moreover, the downstream cholestatic liver injury in both models was indicated to be mediated by the JNK/STAT3 signaling pathway. PMID: 32626965 [PubMed - as supplied by publisher]
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Link: https://doi.org/10.1155/2020/3859472
(Cold Spring Harbor Laboratory) Scientists at Cold Spring Harbor Laboratory found they can stop the growth of pancreatic cancer cells by interfering with the way the cells store cholesterol. Their findings in mice and lab-grown pancreas models point toward a new strategy for treating deadly pancreatic cancer.
Contributors : Mitsuru Tanaka ; Akihito Yasuoka ; Haruka Yoshinuma ; Yoshikazu Saito ; Tomiko Asakura ; Soichi TanabeSeries Type : Expression profiling by arrayOrganism : Rattus norvegicusDespite a variety of seasoning ingredients in diets, little is known about their cooperative effect on animal metabolism. We fed rats a diet containing 30 wt.% instant noodle with a 26% fat-to-energy ratio for 30 days (N-group). Compared with rats that were fed the same diet without seasonings (C-group), the N-group showed lower liver triacylglycerol levels and higher fecal cholesterol levels. To assess the mechanisms underlying this phen...