Genetic variations in the host dependency factors ALCAM and TPST2 impact HIV-1 disease progression

Conclusion: Our data demonstrate that ALCAM and TPST2 play a role in HIV-1 pathogenesis. SNPs in these genes, without known functional implications, had a major effect on disease progression, and therefore, these HDFs may be attractive and effective targets for new treatment strategies.
Source: AIDS - Category: Infectious Diseases Tags: BASIC SCIENCE Source Type: research