Biomarkers of placental redox imbalance in pregnancies with preeclampsia and consequent perinatal outcomes.
CONCLUSION: PE-derived placentas had high concentrations of some antioxidants (enzymes and thiols), which might be a compensation mechanism against oxidative stress. Placental GSH levels were the only biomarker, among the studied ones, related positively with beneficial perinatal outcomes, suggesting that this endogenous antioxidant plays an important role in maintaining the health of the conceptus and women with PE.
PMID: 32592803 [PubMed - as supplied by publisher]
Source: Archives of Biochemistry and Biophysics - Category: Biochemistry Authors: Ferreira RC, Fragoso MBT, TenĂ³rio MCDS, Martins ASDP, Borbely AU, Moura FA, Goulart MOF, Oliveira ACM Tags: Arch Biochem Biophys Source Type: research
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