Anti-fibrotic effect of iguratimod on pulmonary fibrosis by inhibiting the fibroblast-to-myofibroblast transition.

CONCLUSIONS: Our results collectively revealed the beneficial effect of IGU on the inhibition of FMT, thus suggesting that it might act as an effective anti-fibrotic agent in preventing the progression of PF.
PMID: 32590154 [PubMed - as supplied by publisher]

Source: Advances in Medical Sciences - June 22, 2020 Category: Biomedical Science Authors: Lin H, Wu C, Zhu F, Zhang G, Xie Y, Cui Y, Dong G, Zhang X Tags: Adv Med Sci Source Type: research