COVID-19 chilblain-like lesion: immunohistochemical demonstration of SARS-CoV-2 spike protein in blood vessel endothelium and sweat gland epithelium in a PCR-negative patient.

COVID-19 chilblain-like lesion: immunohistochemical demonstration of SARS-CoV-2 spike protein in blood vessel endothelium and sweat gland epithelium in a PCR-negative patient. Br J Dermatol. 2020 Jun 25;: Authors: Santonja C, Heras F, Núñez L, Requena L Abstract A 35-year-old woman with no significant previous medical history presented at the Emergency Department of Fundación Jiménez Díaz Hospital (Madrid, Spain) on April 14th with acral purpuric lesions of three weeks duration. These had started as oedematous, erythematous areas and had appeared coincidentally with fever and coughing, which lasted only two days. There was no history of diarrhoea, ageusia, hyposmia or dyspnea. The patient stated that the skin of her feet acquired a bluish discoloration after standing for some time. PMID: 32585767 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research