Mathematical modeling of PDGF-driven glioma reveals the dynamics of immune cells infiltrating into tumors.

CONCLUSIONS: The chemoattractant gradient field produced by tumor cells may facilitate immune cells migration to the tumor cite. The chemoattractant production rate may be utilized to classify wtIDH1 and muIDH1 tumors. The dynamics of immune cells infiltrating into tumors is largely determined by tumor cell chemoattractant production rate and chemotactic coefficient. PMID: 32585427 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32585427?dopt=Abstract

Source: Neoplasia - June 21, 2020 Category: Cancer & Oncology Authors: Niu B, Zeng X, Phan TA, Szulzewsky F, Holte S, Holland EC, Tian JP Tags: Neoplasia Source Type: research