Curb the symptoms of non-alcoholic fatty liver disease by adopting a Mediterranean diet
(Natural News) Multiple studies have found that eating more fish and plant-based foods like fruits, vegetables and whole grains — typical components of the Mediterranean diet — contribute to good health even in old age. According to Harvard Medical School researchers, people who stick to a Mediterranean diet have a 46 percent higher chance of healthy...
Publication date: Available online 27 June 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Luca Miele, Valentina Giorgio, Antonio Liguori, Salvatore Petta, Roberta Pastorino, Dario Arzani, Maria A. Alberelli, Consuelo Cefalo, Giuseppe Marrone, Marco Biolato, Gianludovico Rapaccini, Stefania Boccia, Antonio Gasbarrini, Antonio Craxì, Antonio Grieco
Publication date: Available online 27 June 2020Source: Journal of Taibah University Medical SciencesAuthor(s): Marwan S. Al-Nimer, Vian A. Esmail, Dler S. Hamid, Mohammad O. Mohammad
bbraio Obesity is recognised as a risk factor for many types of cancers, in particular hepatocellular carcinoma (HCC). A critical factor in the development of HCC from non-alcoholic fatty liver disease (NAFLD) is the presence of non-alcoholic steatohepatitis (NASH). Therapies aimed at NASH to reduce the risk of HCC are sparse and largely unsuccessful. Lifestyle modifications such as diet and regular exercise have poor adherence. Moreover, current pharmacological treatments such as pioglitazone and vitamin E have limited effects on fibrosis, a key risk factor in HCC progression. As NAFLD is becoming more prevalent in de...
Increased intestinal permeability plays a key role in the pathogenesis of fat deposition in the liver. The aim of our study was to assess whether a single nucleotide polymorphism of protein tyrosine phosphatase non-receptor type 2 (PTPN2) (rs2542151 T →G), involved in intestinal permeability, may be associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM).
While one third of the world ’s population is overweight or obese, the impact of obesity as an epigenetic trait affecting not only people’s health but also health of unborn children is highly questionable. Obesity confers a higher risk of developing metabolic diseases such as non-alcoholic fatty liver disease (NAFLD), and a lso of developing hepatocellular carcinoma (HCC) . Besides that, offspring of obese mothers are known to be more susceptible to NAFLD, but no relationship has been established between obesity in mothers and the risk of the progeny to develop HCC .
Conclusions: NAFLD-related HCCs were more often detected at an advanced stage with infiltrative patterns, although they showed no significant difference in survival compared to ALD-related or HBV-related HCCs. A future prospective research should be focused on identifying NAFLD patients who require strict surveillance in order to early detect and timely treat HCC. PMID: 32566546 [PubMed - in process]
The effect of lncRNA FTX on non-alcoholic fatty liver disease (NAFLD) conversion to hepatocellular carcinoma (HCC) is unclear.
Association of serum zinc-α2-glycoprotein with non-alcoholic fatty liver disease. Chin Med J (Engl). 2020 Jun 24;: Authors: Qi XY, Li JY, Wang YD, Zeng YW, Liao ZZ, Ran L, Yang J, Wen GB, Liu JH, Xiao XH PMID: 32590463 [PubMed - as supplied by publisher]
This study aimed to investigate the relati...