Cardiac injury and ARDS meta-analysis validity – Correspondence in response to Santoso et al.

In the course of writing a rapid review for the University of Oxford, we came across an interesting and timely systematic review and meta-analysis in the American Journal of Emergency Medicine by and colleagues [1]. This paper was of note to us because it included a meta-analysis on acute respiratory distress syndrome (ARDS) and cardiac injury, based on two papers - one by Shi [2] and another by Wu [3]. On reading the paper by Wu, we have significant concerns about the inclusion of this study in Santoso's meta-analysis as we believe it currently underpins an inaccurate conclusion that cardiac injury is not significantly associated with increased risk of ARDS in COVID-19 by Santoso.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research