The Influence of Biomechanical Stability on Bone Healing and Fracture-Related Infection: The Legacy of Stephan Perren.

For many centuries, fracture care consisted almost exclusively of conservative treatment options, limited to casting or skeletal traction (1). The concept of open reduction and stable internal fixation (ORIF), heavily influenced by the Association for Internal Fixation (AO/ASIF, "Arbeitsgemeinschaft f ür osteosynthesefragen, later in 1984 to become the AO Foundation), gained popularity in the 1960s as a means to restore anatomical alignment and allow early functional mobilization (2, 3). By minimizing the sequelae of extended immobilization, such as joint stiffness and muscle atrophy, internal f ixation of fractures accelerated the process of rehabilitation towards complete recovery (1).

Source: Injury - June 25, 2020 Category: Orthopaedics Authors: Andrew L. Foster, T. Fintan Moriarty, Charalampos Zalavras, Mario Morgenstern, Anjali Jaiprakash, Ross Crawford, Marc-Antoine Burch, Willemijn Boot, Kevin Tetsworth, Theodore Miclau, Peter Ochsner, Michael A. Schuetz, R. Geoff Richards, Willem-Jan Metsema Source Type: research