Parkinson’s disease - the ‘practically inevitable’ sexual symptom you may be missing

PARKINSON'S disease symptoms develop slowly over a long time, and could be caused by nerve damage in the brain. One of the more common warning signs of the brain condition includes changes to your sex drive, and erectile dysfunction. These are the "practically inevitable" sexual symptoms of Parkinson's you should know.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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AbstractBackgroundSexual dysfunction (SD) is a common, yet under-reported, non-motor symptom (NMS) of Parkinson ’s disease (PD). The present study investigated the sexual functions in PD male patients, its correlation with motor and other NMSs, and their impact on health-related quality of life (HRQoL).MethodsThe sexual functions of 40 PD male patients were assessed using the International Index of Erectile Function (IIEF) and compared to 25 healthy age-matched controls. Patients were evaluated using the NMS Scale (NMSS) and the Arabic version of the Parkinson ’s-Disease Questionnaire (PDQ-39). We compared the ...
Source: Neurological Sciences - Category: Neurology Source Type: research
Authors: Quarracino C, Otero-Losada M, Capani F, Pérez-Lloret S Abstract Introduction: Autonomic dysfunction is one of the most frequent and disabling non-motor symptoms of Parkinson's disease (PD). It includes, among others, orthostatic hypotension (OH), sialorrhea, constipation, erectile dysfunction (ED), urinary dysfunction, and diaphoresis. They are usually under-recognized and suboptimally managed.Areas covered: Recommended treatments for dysautonomias are summarized with a description of the mechanism of action and observed results. The pathophysiology of each disorder is reviewed to pinpoint possible ...
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Men’s sexual health and wellness company, Morari Medical is using neuromodulation for its wearable device to help treat premature ejaculation (PE). The Maple Grove, MN-based company debuted a prototype of the patch-like device at the Consumer Electronics Show in Las Vegas earlier this month. Morari was one of 10 companies in the emerging sextech market to have a presence at the show. Jeff Bennett, the company’s founder and CEO spoke with MD+DI about the Morari Medical and its mission. “Specifically, we’re trying to address the medical condition of PE, ...
Source: MDDI - Category: Medical Devices Authors: Tags: Electronics Source Type: news
Abstract Parkinson's disease (PD) is a neurodegenerative disease with a 200 year-long research history. Our understanding about its clinical phenotype and pathogenesis remains limited, although dopaminergic replacement therapy has significantly improved patient outcomes. Autonomic dysfunction is an essential category of non-motor phenotypes that has recently become a cutting edge field that directs frontier research in PD. In this review, we initially describe the epidemiology of dysautonomic symptoms in PD. Then, we perform a meticulous analysis of the pathophysiology of autonomic dysfunction in PD and propose th...
Source: Neurobiology of Disease - Category: Neurology Authors: Tags: Neurobiol Dis Source Type: research
Conclusions: Early erectile dysfunction may be a premotor symptom of MSA and DLB, reflecting premonitory dysautonomia. It was not associated with premotor PD or PDD. PMID: 31093326 [PubMed]
Source: Parkinsons Disease - Category: Neurology Tags: Parkinsons Dis Source Type: research
Conclusions Dysautonomic symptoms frequently occuring in α-synucleinopathies comprise cardiovascular, gastrointestinal, urogenital and thermoregulatory disturbances. These symptoms reduce quality of life and worsen prognosis. The understanding of their pathophysiology, as well as the detection of α-synuclein deposition and autonomic dysfunction in the premotor stages of α-synucleinopathies may be key for identifying novel treatment targets and improving clinical outcomes. While causative treatment is not yet available, improvement of quality of life can be achieved by personalized symptomatic treatment r...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
AbstractApomorphine is now recognized as the oldest antiparkinsonian drug on the market. Though still underused, it is increasingly prescribed in Europe for patients with advanced Parkinson ’s disease (PD) with motor fluctuations. However, its history is far from being limited to movement disorders. This paper traces the history of apomorphine, from its earliest empirical use, to its synthesis, pharmacological development, and numerous indications in human and veterinary medicine, in light of its most recent uses and newest challenges. From shamanic rituals in ancient Egypt and Mesoamerica, to the treatment of erecti...
Source: Drugs in R&D - Category: Drugs & Pharmacology Source Type: research
Publication date: 2017 Source:International Review of Neurobiology, Volume 134 Author(s): Kalyan B. Bhattacharyya, Miguel Rosa-Grilo Sexual dysfunctions (SDs) are one of the most neglected nonmotor symptoms in Parkinson's disease (PD). A number of reasons including social and cultural factors might explain, at least partially, why SD is still one of the most underrecognized aspects of the condition after 200 years since the very first description by James Parkinson. SD has not been extensively investigated, however, a number of studies have shown a high prevalence of decreased libido, orgasmic dysfunction in both men and ...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
CONCLUSIONS: ED leads to an increased risk of PD. ED patients with diabetes or hypertension have an elevated risk of PD. PMID: 28748676 [PubMed]
Source: Journal of Clinical Neurology - Category: Neurology Tags: J Clin Neurol Source Type: research
Publication date: Available online 27 June 2017 Source:International Review of Neurobiology Author(s): Kalyan B. Bhattacharyya, Miguel Rosa-Grilo Sexual dysfunctions (SDs) are one of the most neglected nonmotor symptoms in Parkinson's disease (PD). A number of reasons including social and cultural factors might explain, at least partially, why SD is still one of the most underrecognized aspects of the condition after 200 years since the very first description by James Parkinson. SD has not been extensively investigated, however, a number of studies have shown a high prevalence of decreased libido, orgasmic dysfunction in ...
Source: International Review of Neurobiology - Category: Neuroscience Source Type: research
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