Surveillance of influenza and other respiratory viruses in the UK: Winter 2019 to 2020, PHE

This report describes influenza activity experienced in UK in the period from week 40, 2019 to week 14, 2020. It includes observations and commentary from the childhood vaccination programme and activity of other seasonal and novel respiratory viruses.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Condition:   Influenza Interventions:   Biological: Flublok Quadrivalent influenza vaccine RIV4;   Biological: Standard-dose quadrivalent inactivated influenza vaccine SD-IIV4 Sponsor:   Sanofi Pasteur, a Sanofi Company Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Credit: United NationsBy Thalif DeenUNITED NATIONS, Jul 8 2020 (IPS) The coronavirus—which has claimed the lives of over 538,000 people and infected more than 11.6 million worldwide—has destabilized virtually every facet of human life ever since its outbreak in late December. Providing a grim economic scenario of the devastation caused by the pandemic– including rising poverty, hunger and unemployment– UN Secretary-General Antonio Guterres warned last week of the possibility of an even worse disaster: the risks of bioterrorist attacks deploying deadly germs. He said it has already shown some of the...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Armed Conflicts Featured Global Global Geopolitics Global Governance Headlines Health IPS UN: Inside the Glasshouse Peace TerraViva United Nations Source Type: news
(eLife) Early infections of influenza A can help predict how the virus will affect people across different ages in the future and could impact the effectiveness of flu vaccines, says a new study published today in eLife.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Seasonal variation in the age distribution of influenza A cases suggests that factors other than age shape susceptibility to medically attended infection. We ask whether these differences can be partly explained by protection conferred by childhood influenza infection, which has lasting impacts on immune responses to influenza and protection against new influenza A subtypes (phenomena known as original antigenic sin and immune imprinting). Fitting a statistical model to data from studies of influenza vaccine effectiveness (VE), we find that primary infection appears to reduce the risk of medically attended infection with t...
Source: eLife - Category: Biomedical Science Tags: Epidemiology and Global Health Microbiology and Infectious Disease Source Type: research
The technology relates to a protein-based nanoparticle platform that allows presentation of immunogenic molecules such as influenza virus antigens. This protein platform is made up of hepatitis B capsid/core proteins. The core proteins contain immunogenic loop c/e1, where other antigens can be inserted and the chimeric protein retains the ability to form capsid-like particles. The technology describes the insertion of one or more copies of influenza epitopes derived from the globular head or the stem region of hemagglutinin protein into or around the c/e1 loop of the core protein. The nanoparticles formed by the use of Hep...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
AbstractPurpose of ReviewTo better understand the impact of obesity and cardiovascular diseases on influenza A infection.Recent FindingsThis infection could have detrimental outcomes in obese patients with cardiovascular diseases, such as an increased risk, length of hospitalization, disease severity, morbidity, and mortality. Nevertheless, there also might be some cardioprotective benefits associated with influenza vaccination, such as a reduced mortality, hospitalization, and acute coronary syndromes, in patients with coronary heart disease and/or heart failure.SummaryObesity negatively impacts immune function and host d...
Source: Current Tropical Medicine Reports - Category: Tropical Medicine Source Type: research
IJERPH, Vol. 17, Pages 4877: The Outcome and Implications of Public Precautionary Measures in Taiwan–Declining Respiratory Disease Cases in the COVID-19 Pandemic International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17134877 Authors: Hsieh Lin Wang Pauleen Chen With the rapid development of the COVID-19 pandemic, countries are trying to cope with increasing medical demands, and, at the same time, to reduce the increase of infected numbers by implementing a number of public health measures, namely non-pharmaceutical interventions (NPIs). These public health measures ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Brief Report Source Type: research
Bilateral shoulder adhesive capsulitis may develop in association with the administration of an influenza vaccine. Vaccine administration should utilize proper technique to avoid injection into the shoulder capsule. AbstractBilateral shoulder adhesive capsulitis may develop in association with the administration of an influenza vaccine. Vaccine administration should utilize proper technique to avoid injection into the shoulder capsule.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
CONCLUSIONS: The P3-MumBubVax intervention is the first Australian antenatal intervention designed to support both maternal and childhood vaccine uptake. A pilot study is underway to inform a planned cluster randomised controlled trial. So what? Barriers to vaccine acceptance and uptake are complex. The P3 model is a promising evidence-informed multi-component intervention strategy targeting all three levels influencing healthcare decision-making. PMID: 32619032 [PubMed - as supplied by publisher]
Source: Health Promotion Journal of Australia - Category: International Medicine & Public Health Tags: Health Promot J Austr Source Type: research
This study conducted an evidence synthesis of various stakeholders ’ (patients, physicians/rheumatologists) perspectives about the determinants of vaccine hesitancy and uptake among patients with RA. We searched three bibliographic and reference databases (PUBMED, PsychINFO, and SCOPUS) for relevant English or French articles published in peer-reviewed journals t hrough July 2019 that conducted either qualitative or quantitative assessments of vaccine hesitancy or uptake. Key themes associated with vaccination hesitancy themes according to different stakeholders were extracted and summarized. Of 783 unique citations,...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
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