Intravenous ketorolac is associated with reduced mortality and morbidity after open abdominal aortic aneurysm repair.

CONCLUSION: This study demonstrated 40% mortality reduction with intravenous ketorolac following open abdominal aortic aneurysm repair. The survival benefit could be due to its anti-inflammatory and opioid-sparing properties. This is evident by its protective effect against respiratory outcomes. The lack of association with the classical non-steroidal anti-inflammatory drugs-related cardiac and hemorrhagic complication could be attributable to the short-term use of ketorolac compared with non-steroidal anti-inflammatory drugs chronic use. PMID: 32576118 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32576118?dopt=Abstract

Source: Vascular - June 22, 2020 Category: Surgery Authors: Nejim B, Weaver ML, Locham S, Al-Nouri O, Naazie IN, Malas MB Tags: Vascular Source Type: research