Characterization of the Inflammatory Response to Severe COVID-19 Illness.

CONCLUSIONS: The COVID-19 cytokinemia is distinct from that of other types of pneumonia leading to organ failure and ICU need. Neutrophils undergo immunometabolic reprogramming in severe COVID-19 illness. Cytokine ratios may predict outcomes in this population. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/). PMID: 32584597 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32584597?dopt=Abstract

Source: American Journal of Respiratory and Critical Care Medicine - June 24, 2020 Category: Respiratory Medicine Authors: McElvaney OJ, McEvoy N, McElvaney OF, Carroll TP, Murphy MP, Dunlea DM, Ní Choileáin O, Clarke J, O'Connor E, Hogan G, Ryan D, Sulaiman I, Gunaratnam C, Branagan P, O'Brien ME, Morgan RK, Costello RW, Hurley K, Walsh S, de Barra E, McNally C, McConkey S Tags: Am J Respir Crit Care Med Source Type: research