Model May Help Predict Risk for Testing Positive for COVID - 19

Risk reduced with pneumococcal polysaccharide, flu vaccine; melatonin, paroxetine, or carvedilol use
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Infections, Internal Medicine, Critical Care, Emergency Medicine, Pathology, Pharmacy, Pulmonology, Journal, Source Type: news

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Over the past few months, we have all seen the results of significant disruption to daily life due to the COVID-19 pandemic, high levels of unemployment, and civil unrest driven by chronic racial injustice. These overlapping waves of societal insult have begun to bring necessary attention to the importance of health care disparities in the United States. Direct links between stress, discrimination, racial injustice, and health outcomes occurring over one’s lifespan have not been well studied. But a recently published article in the journal Hypertension has looked at the connection between discrimination and increased...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health care disparities Hypertension and Stroke Source Type: blogs
While the world waits for a COVID-19 vaccine, children across the globe are going without shots already known to be life-saving. With the world in disarray due to the COVID-19 pandemic, the number of children vaccinated this year against infections like diphtheria, tetanus, pertussis, measles and pneumococcal disease has fallen to levels not seen since the 1990s, according to a new report from the Bill and Melinda Gates Foundation. “In other words,” the report reads, “we’ve been set back about 25 years in about 25 weeks.” That stark figure comes from the Gates Foundation’s annual Goalkee...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
CONCLUSIONS: Willingness to receive a COVID-19 vaccination is currently high among high-risk individuals. Mass media interventions aimed at maximizing vaccine uptake should utilize the BCTs of information about health, emotional, social and environmental consequences, and salience of consequences. PMID: 32889759 [PubMed - as supplied by publisher]
Source: British Journal of Health Psychology - Category: Psychiatry & Psychology Authors: Tags: Br J Health Psychol Source Type: research
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit. Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The national immunisation programme is highly successful in reducing the incidence of serious and sometimes life-threatening diseases such as pneumococcal and meningococcal infections, whooping cough, diphtheria and measles. It remains important to maintain the best possible vaccine uptake to prevent a resurgence of these infections. This will also prevent increasing further the numbers of patients requiring health services, as well as outbreaks of vaccine-preventable diseases, and allow us to provide important protection to children and other vulnerable groups. Where possible, the routine immunisation programmes should be...
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
The present Editorial highlights a study by Aliu and colleagues, entitled “Selective inhibition of anti‐MAG IgM autoantibody binding to myelin by an antigen specific glycopolymer” published in the current issue of the Journal of Neurochemistry, in which the authors have developed a therapy directed to a highly specific target to treat a rare neurologic disease where a carbohydrate component of the myelin sheath is attacked by antibody. The targeted therapy specifically blocks the antibody from binding to a particular sugar on the myelin sheath. The authors' findings are applicable to a parallel strategy for t...
Source: Journal of Neurochemistry - Category: Neuroscience Authors: Tags: EDITORIAL HIGHLIGHT Source Type: research
We present sensitivity, specificity, negative predictive value, and positive predictive value at different prediction cut-offs.The calculator is freely available at https://riskcalc.org/COVID19. INTERPRETATION: Prediction of a COVID-19 (+) test is possible and could help direct healthcare resources. We demonstrate relevance of age, race, gender, and socioeconomic characteristics in COVID-19-susceptibility and suggest a potential modifying role of certain common vaccinations and drugs identified in drug-repurposing studies. PMID: 32533957 [PubMed - as supplied by publisher]
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitoch...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
By ANISH KOKA, MD A number of politically tinged narratives have divided physicians during the pandemic. It would be unfortunate if politics obscured the major problem brought into stark relief by the pandemic: a system that marginalizes physicians and strips them of agency. In practices big and small, hospital-employed or private practice, nursing homes or hospitals, there are serious issues raising their heads for doctors and their patients. No masks for you When I walked into my office Thursday, March 12th, I assembled the office staff for the first time to talk about COVID.  The prior weekend had been...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: COVID-19 Medical Practice Physicians Anish Koka medical autonomy Pandemic Source Type: blogs
Alex Nowrasteh andAndrew C. ForresterThe international spread of the SARS ‐​CoV‐​2 virus that causes the disease COVID-19 has prompted many governments to close their borders. Immigration policy plays an important role in limiting the international spread of contagious diseases.Prior to the COVID-19 crisis,several commentators were concerned that immigrants – especially illegal immigrants – were spreading serious diseases in the United States. This blog post is the first in a series to answer the question of whether immigrants spread serious notifiable diseases other than COVID-19 in the ...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
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