TRPML1ng on sparks.

TRPML1ng on sparks.
Sci Signal. 2020 Jun 23;13(637):
Authors: Nieves-Cintron M, Santana LF, Navedo MF
Abstract
In this issue of Science Signaling, Thakore et al. report that the Ca2+-permeable channel TRPML1 closely associates with ryanodine receptors to induce Ca2+ sparks in native arterial myocytes. Functional studies revealed a key role for TRPML1 channels in regulation of arterial myocyte contractility and blood pressure.
PMID: 32576679 [PubMed - in process]

Source: Science Signaling - June 22, 2020 Category: Biomedical Science Authors: Nieves-Cintron M, Santana LF, Navedo MF Tags: Sci Signal Source Type: research