TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies.
In conclusion, functional TLR3 was broadly expressed by maternal and fetal cells at both sites of the maternal-fetal interface and the placental intravillous expression was increased in preeclampsia. This suggests TLR3-mediated inflammatory involvement with local regulation at both sites of the maternal-fetal interface in normal and preeclamptic pregnancies.
PMID: 32573856 [PubMed - as supplied by publisher]
Source: Journal of Leukocyte Biology - Category: Hematology Authors: Gierman LM, Silva GB, Pervaiz Z, Rakner JJ, Mundal SB, Thaning AJ, Nervik I, Elschot M, Mathew S, Thomsen LCV, Bjørge L, Iversen AC Tags: J Leukoc Biol Source Type: research