Airborne particulate matter from goat farm increases acute allergic airway responses in mice.

Conclusions: A single exposure to goat farm BioPM enhanced airway inflammation in both saline and OVA-challenged allergic mice, with neutrophilic response as Th17 disorder and eosinophilic response as Th2 disorder indicative of the severity of allergic responses. Identification of the mode of action by which farm PM interacts with airway allergic pathways will be useful to design potential therapeutic approaches. PMID: 32571132 [PubMed - as supplied by publisher]
Source: Inhalation Toxicology - Category: Respiratory Medicine Tags: Inhal Toxicol Source Type: research