Periostin in middle ear mucosa according to eosinophilic otitis media severity: Middle ear pathology-based treatment

Eosinophilic otitis media (EOM) is an intractable disorder associated with bronchial asthma and chronic rhinosinusitis with nasal polyposis. Periostin is an extracellular matrix protein secreted by fibroblasts in response to interleukin (IL)-4 and/or IL-13 and is a known marker for eosinophilic disorders. We assessed serum periostin levels and expression of periostin in the middle ear mucosa according to three grade of EOM severity (grade1 to 3).
Source: Auris, Nasus, Larynx - Category: ENT & OMF Authors: Source Type: research