Fat grafting: Early hypoxia, oxidative stress, and inflammation developing prior to injection

Autologous fat grafting is widely used during plastic surgery but unpredictable fat retention remains a major concern. Although many studies have explored whether fat harvesting, processing, and injection affect adipocyte viability, the oxygenation and inflammatory status of grafted fat remain unknown. Unlike vascularized tissue transfer, fat grafting is a non-vascular procedure. Fat initially lacks vascular support and receives oxygen and nutrients only via diffusion until neovascularization develops.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - Category: Cosmetic Surgery Authors: Tags: Correspondence and Communications Source Type: research