Current serotype of dengue virus in Singapore disguises itself to evade vaccines and therapeutics

(Duke-NUS Medical School) Singapore saw 1,158 dengue cases in the week ending 13 June 2020, the highest number of weekly dengue cases ever recorded since 2014*. The dengue virus serotype 3 (DENV3), which is currently circulating in Singapore, can undergo dramatic structural changes that enable it to resist vaccines and therapeutics, reveal findings from a study by scientists from Duke-NUS Medical School. The findings, published in Nature Communications, could guide the development of effective vaccines and therapeutics against dengue infection.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news