MicroRNA-145 suppresses uveal melanoma angiogenesis and growth by targeting neuroblastoma RAS viral oncogene homolog and vascular endothelial growth factor.

CONCLUSION: Our results indicated that miR-145 is an important tumor suppressor and the inhibitory strategies against N-RAS/VEGF signaling pathway might be potential therapeutic applications for UM in the future.
PMID: 32568870 [PubMed - as supplied by publisher]

Source: Chinese Medical Journal - June 18, 2020 Category: General Medicine Authors: Yang JY, Li Y, Wang Q, Zhou WJ, Yan YN, Wei WB Tags: Chin Med J (Engl) Source Type: research