Evaluation of serum-based real-time PCR to detect Schistosoma mansoni infection before and after treatment

ConclusionsThe data presented here show that the serum-based real-time PCR exhibits excellent diagnostic accuracy, in contrast to the use of urine as sample material forS. mansoni DNA detection. However, as circulating DNA does not necessarily reflect the persistence of living worms in schistosomiasis, this method is less well suited to verify the success of treatment with praziquantel.
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research