Inhibition of berberine hydrochloride on Candida albicans biofilm formation.

CONCLUSION: The efficacy of BH in inhibiting the formation of C.albicans biofilm by killing the cells in the biofilm and destroying its structure; and the mechanism may be to down-regulate the expression of EFG1, HWP1, ECE1, and ALS1 in hyphae formation, thereby, retarding the morphological transformation of C. albicans.
PMID: 32557120 [PubMed - as supplied by publisher]

Source: Biotechnology Letters - June 14, 2020 Category: Biotechnology Authors: Huang X, Zheng M, Yi Y, Patel A, Song Z, Li Y Tags: Biotechnol Lett Source Type: research