Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation

Ischemic stroke is a devastating disease without a cure. The available treatments for ischemic stroke, thrombolysis by tissue plasminogen activator, and thrombectomy are suitable only to a fraction of patients...

Source: Journal of Neuroinflammation - June 19, 2020 Category: Neurology Authors: Natalia Kolosowska, Maria Gotkiewicz, Hiramani Dhungana, Luca Giudice, Rosalba Giugno, Daphne Box, Mikko T. Huuskonen, Paula Korhonen, Flavia Scoyni, Katja M. Kanninen, Seppo Yl ä-Herttuala, Tiia A. Turunen, Mikko P. Turunen, Jari Koistinaho and Tarja Ma Tags: Research Source Type: research