Combination of computed tomography-guided iodine-125 brachytherapy and bronchial arterial chemoembolization for locally advanced stage III non-small cell lung cancer after failure of concurrent chemoradiotherapy11Abbreviations: BAI, bronchial arterial infusion; BACE, bronchial arterial chemoembolization; CR, complete response; CT, computed tomography; D90, dose covering 90% of the target volume; NSCLC, non-small cell lung cancer; OS, overall survival; PR, partial response; PFS, progression-free survival; PD, progressive disease; SD, stable disease; TPS, treatment planning system

Lung cancer is the leading cause of cancer-related death worldwide. Owing to the lack of modalities for early diagnosis, 75 % of lung cancer patients are diagnosed at the advanced stage of the disease and, thus, cannot undergo resection [1]. Non-small cell lung cancer (NSCLC) accounts for 80 –85 % of all cases of lung cancer. The first-line standard treatment for advanced inoperable NSCLC is combined chemoradiotherapy [2]. However, treatment failure is noted in some patients, and those who undergo chemoradiotherapy as second-line therapy still have short overall survival (OS) and poor prognosis [3].
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research