SRPX2 promotes cell proliferation and invasion via activating FAK/SRC/ERK pathway in non-small cell lung cancer.

CONCLUSION: Taken together, our findings revealed a functional role of SRPX2 in NSCLC cell proliferation, migration and invasion. The underlying mechanism was, at least partially, the activation of FAK/SRC/ERK pathway. This study provides the molecular basis for targeting SRPX2 in potential clinical application for NSCLC.
PMID: 32550700 [PubMed - as supplied by publisher]

Source: Acta Biochim Pol - June 17, 2020 Category: Biochemistry Authors: Li X, Liu J, Sun H, Zou Y, Chen J, Chen Y, Chen C, Wu X Tags: Acta Biochim Pol Source Type: research