Clinical characteristics and prenatal diagnosis for 22 families in Henan Province of China with X-linked agammaglobulinemia (XLA) related to Bruton ’s tyrosine kinase (BTK) gene mutations
X-linked agammaglobulinaemia (XLA) is a rare immunodeficiency disease for which recurrent severe infection is the major clinical symptom. BTK is the main causative gene, with X chromosome recessive inheritance. H...
Source: BMC Medical Genetics - Category: Genetics & Stem Cells Authors: Shanshan Gao, Shuang Hu, Huikun Duan, Li Wang and Xiangdong Kong Tags: Research article Source Type: research