Population-based case-finding to identify subjects with undiagnosed asthma or COPD

Conclusion 20% of randomly selected individuals who report respiratory symptoms in Canada have undiagnosed airflow obstruction due to asthma or COPD. Questionnaires could exclude subjects at low risk but lack the ability to accurately find subjects with undiagnosed disease.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: COPD and smoking, Asthma and allergy Original Articles: Asthma and COPD Source Type: research

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This study analyzed cross-sectional datasets of adults (aged ≥ 40 years) in the Korean National Health and Nutrition Examination Survey 2010-2016. Health-related QoL was assessed using the 3-level EuroQoL 5-dimension component (EQ-5D-3L) index score. The presence of chronic cough and other conditions were defined using structured questionnaires. RESULTS: The prevalence of chronic cough was 3.48% ± 0.17% among adults aged ≥ 40 years. The overall EQ-5D-3L index score was significantly lower in subjects with than without chronic cough (0.79 ± 0.01 vs. 0.86 ± 0.00, P
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Authors: Kim SR, Park KH, Son NH, Moon J, Park HJ, Kim K, Park JW, Lee JH Abstract PURPOSE: It is difficult to assess airway obstruction using spirometry in adult asthmatic patients with preserved lung function. Impulse oscillometry (IOS) can detect not only airway resistance but also reactance. Therefore, IOS may be useful in assessing pulmonary function in such patients. We investigated the applicability of IOS for asthma patients with preserved lung function. METHODS: Between 2015 and 2018, 1,248 adult asthmatic patients suspected of having asthma who visited the Allergy and Asthma Center of Severance Hospit...
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Since the first case of severe acute respiratory syndrome coronavirus 2 infection on January 22, 2020, the number of positive cases and deaths has rapidly increased.1 The initial report of 140 hospitalized patients infected with coronavirus disease 2019 (COVID-19) from Wuhan, China, indicated that allergic diseases, asthma, and chronic obstructive pulmonary diseases were not risk factors for severe acute respiratory syndrome coronavirus 2 infection.2 However, the clinical features of this condition with cough and shortness of breath (SOB) might mask, or mimic, an asthma exacerbation.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Since the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on January 22, 2020, the number of positive cases and deaths has rapidly increased.(1) The initial report of 140 hospitalized coronavirus (COVID-19) infected patients from Wuhan China indicated that allergic disease, asthma and chronic obstructive pulmonary disease were not risk factors for SARS-CoV-2 infection.(2) However, the clinical features of this condition with cough and shortness of breath might mask, or mimic, an asthma exacerbation.(3) Given the evolving nature of this pandemic, this initial summary may not represent the clinical...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Conclusions: There was increased burden of respiratory problems and lower lung volumes and flows among traffic policemen.
Source: Indian Journal of Community Medicine - Category: International Medicine & Public Health Authors: Source Type: research
Background: Allergic respiratory disorders often co-exist, but little is known about their specific patterns, exposure profiles or COPD risk.Objectives: To identify latent patterns of allergic respiratory disorders and their exposure profiles and COPD risk.Methods: Latent patterns of current asthma, hayfever, eczema, food allergy with their ages at onset, chronic cough, chronic sputum and allergic sensitivities were identified, using latent class analysis (LCA), among 3608 participants from the Tasmanian Longitudinal Health Study (mean age: 53 years), and cross-sectionally associated with exposures and COPD risk.Results: F...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Mario Malerba1,2*, Valentina Foci1,2, Filippo Patrucco1,2, Patrizia Pochetti1,2, Matteo Nardin3, Corrado Pelaia4 and Alessandro Radaeli5 1Respiratory Medicine, Department of Translational Medicine, University of Eastern Piedmont, Vercelli, Italy 2Respiratory Unit, Sant’Andrea Hospital, Vercelli, Italy 3Department of Medicine, Spedali Civili di Brescia, Brescia, Italy 4Department of Medical and Surgical Sciences, Section of Respiratory Diseases, University “Magna Græcia” of Catanzaro, Catanzaro, Italy 5Department of Emergency, Spedali Civili di Brescia, Brescia, Italy Chronic obstructiv...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
This study evaluated the effects of dried ginger and LGWWJX decoction on cold asthma at the metabolomics level. It provides a reference for the research on the compatibility of Chinese Medicine. Introduction Ginger is a Chinese medicine (CM) used as a food and as a medicine, and is often used to treat cold syndrome through the property of warming. Dried ginger (Zingiberis Rhizoma, GanJiang, GJ) is processed from fresh ginger and is also commonly used in CM. It is used to treat cold asthma by “warming the stomach to dispel cold, warming the lung to resolve fluid,” and it has significant anti-inflammatory...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Discussion There are numerous microbial communities inhabited in the human body, which is critical to human health. The relationship between human microbiome and diseases received much attention from both medical and bioinformatics community recently. However, traditional methods to detect their association is costly and labor-intensive. Thus, we proposed here a new computational model called NBLPIHMDA to infer potential microbe-disease associations. NBLPIHMDA first combined known microbe-disease associations in HMDAD and the Gaussian interaction profile kernel similarity to construct disease similarity network and microb...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion Human microbiome is normal flora for humans, which has been proved to be of symbiotic relationship with humans and harmless to humans. If the microbes that breed in the human body become “unhealthy,” it will definitely affect the host's physical condition. People are continuing to explore the pathologic relationship between microorganisms and the human body through high-throughput sequencing technologies and analysis systems. However, it is a pity that their pathogenesis cannot be fully understood as yet. Considering that relying only on conventional experimental methods is time-consuming an...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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